Nutsche filter reactor suppliers from China: The new version of GMP puts forward higher requirements for the production of APIs and related equipment. It is obvious that equipment is the key to ensuring the quality of APIs and their production stability. After the material enters, parts in the equipment that are directly exposed to the material include the functional nozzle, the inner wall, the stirring mechanism, the filtering mechanism, the filtrate channel, the filtering component and the discharge valve mechanism. Among them, except for the stirring mechanism, the others are all static. Equipped by the correct materials, with proper manufacturing process, these parts will not bring any foreign matter into the process. However, the stirring mechanism is moving. First, it needs to use clean-grade mechanical seal of main shaft to realize good sealing performance. An isolation cavity is set in the mechanical seal to prevent any impurities that may be generated by the environment or the mechanical seal itself from entering the equipment. Secondly, as there is no rotating fulcrum at the bottom of Conical Filter Dryer for stirring mechanism, which is designed with suspension concept, it fundamentally eliminates the possibility of contamination by impurities. Read even more details at agitated nutsche filter dryer.
The stirring device is usually a mechanical paddle or impeller that is driven by an external motor and connected to the reactor wall. This creates agitation within the tank by circulatory motion, which helps homogenize the materials much more quickly than traditional open systems. As a result, reactions between different components occur more rapidly and at lower temperatures than in other reactors, saving energy and increasing efficiency. The CSTR also offers superior safety compared to other reactors due to its closed-system design. In addition, this type of reactor can be operated at higher pressures than open systems, allowing for better control over reaction conditions and greater product yields.
The agitated nutsche filter component of this equipment allows for efficient solid-liquid separation. The slurry or liquid mixture is introduced into the vessel, and the agitator stirs, mixes, or agitates the contents. This agitation enhances the filtration process by promoting the separation of solids from the liquid phase. The liquid passes through the filter medium, while the solids form a cake on top of it. Once the filtration process is complete, the filter dryer component comes into play. The retained filter cake is subjected to drying operations to remove moisture and achieve the desired level of dryness. Various methods can be employed, such as applying heat, vacuum, or a combination of both. The integrated drying capability of the filter dryer ensures efficient evaporation of moisture from the filter cake.
Wuxi Zhanghua Pharmaceutical Equipment Co.,Ltd was founded in 1976, committed to researching, developing and manufacturing reaction, crystallization, filtration, drying equipment. With the development of the leading technologies for more than 40 years, our engineering equipment is not only for the pharmaceutical industry, but also for fine chemicals, pesticides, new energy, new materials and other industries. We customize the integrated solution of reaction, crystallization, filtration and drying process equipment for clients.
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Biological fermentation technology offers efficiency, environmental friendliness, and sustainability. By optimizing fermentation conditions and selecting suitable organisms, it is possible to increase yields and product quality while reducing resource consumption and waste generation. Thus, biological fermenters play a crucial role in achieving sustainable development goals and meeting the growing demands of society. The V-type mixer is a type of industrial mixing equipment commonly used in various industries such as food processing, pharmaceuticals, and chemicals. It is designed to efficiently blend dry or wet materials together to achieve a homogeneous mixture. The V blender machine has its name from its distinctive V-shaped container or trough, which is usually made of stainless steel or other durable materials. The V-shape facilitates efficient mixing by creating a tumbling action of the materials inside the container. This design ensures that all particles come into contact with each other, resulting in thorough blending.
The mixer operates by rotating the V-shaped container on its axis. The rotation causes the materials to move in a complex motion, which includes rolling, cascading, and crossing over each other. As a result, the materials are constantly being intermixed and distributed evenly throughout the container. V type blenders are known for their versatility and ability to handle a wide range of materials, including powders, granules, pastes, and viscous liquids. They are particularly effective at blending materials with different particle sizes and densities. The mixing process can be further enhanced by incorporating additional features such as intensifier bars or choppers to break up agglomerates or lumps.
The operator and product safety are prioritized, and the dryer is designed to be flexible in its applications. It can accommodate a filling volume ranging from 10% to 100% of the total workload. With its large capacity, the dryer enables efficient solvent recovery while consuming low drive power compared to other models. The drying process is gentle, and there is no bottom bearing, allowing for easy discharge and cleaning with a working volume of up to 6ml. The sealing system ensures safety and compliance with ATEX standards, and various sealing materials can be utilized. After drying, there is no need for an additional shredder.
